Rabbit의 tibia에 매식된 titanium시편 내부에 설치한 희토류 자석의 자성이 주위의 골형성에 미치는 영향에 관한 연구
The effect of magnetism(Neodymium magnet) on bone formation around titanium implants inserted into the tibia of rabbit
박명원, 이성복, 최대균, 권긍록,
소속 상세정보
박명원 ( Park Myung-Won ) - 경희대학교 치과대학 치과보철학교실
이성복 ( Lee Sung-Bok ) - 경희대학교 치과대학 치과보철학교실
최대균 ( Choi Dae-Gyun ) - 경희대학교 치과대학 치과보철학교실
권긍록 ( Kwon Kung-Rock ) - 경희대학교 치과대학 치과보철학교실
KMID : 0362420050430040519
Abstract
Statement of problem: There are many articles that showed that the magnetism affected the bone formation around titanium implant. It means that a proper magnetism made the osseointegration improved around the implant. So after additional research on the other effect of magnetism on bone formation in implant therapy, we can conclude its possibility of clinical application on implant treatment.
Purpose: The purposes of this study were to find out the intensity of magnetic field where magnetism in the titanium implant specimen inserted into the bone could affect the bone formation, and to discover the possibility of clinical application in the areas of dental implants and bone grafts.
Materials & Methods: Ten adult male rabbits(mean BW 2Kg) were used in this study. Titanium implant specimens were surgically implanted on the mesial side of the tibia of rabbits. Neodymium magnets(Magnedisc 500, Aichi Steel Corp. Japan) were placed into the implants of experimental group except control group, just after placement of the titanium implants. At 2, 4 and 8 weeks after the surgery, the animals were sacrificed, specimens were obtained and stained with Hematoxylin-Eosin for light microscopic evaluation and histomorphometric analysis.
Conclusion: The results were as follows: 1. In radiographic findings, increased radiopacity downward from crestal bone was observed along the titanium implant specimen at experimental period passed by 2,4, and 8 weeks in both control and experimental group. 2. In histoiogic findings, increased new bone formation was shown in both control and experimental group through the experiment performed for 2,4, and 8 weeks. More new bone formation and bone remodeling were shown in experimental group. 3. In histomorphometric analysis, the bone contact ratios were 11.9% for control group and 38.5% for experimental group(p<0.05).
키워드
Neodymium magnet;titanium implant;Histomorphometric analysis;New bone formation;Bone remodeling;Electromagnetic field
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